From the "Playing the Game" section:
The game requires two distinct roles. The game master creates the adventures and adjudicates the actions of the monkeys. The players control the actions of a single monkey and attempt to complete the mission created by the game master.
Each monkey has a handler. Monkeys are typically deployed in a squad of two to five animals. Their mission parameters may vary depending on the status of the received threat. In some cases they may be searching a location to find a potential threat while in others they may simply be dispatched to remove an already located threat. They are expected to operate in both occupied and unoccupied areas, although they are more often deployed following an evacuation of the area.
The monkeys operate with three key rules: follow the orders of your handler, preserve yourself when possible, and always remove the threat. How well the monkeys follow these three rules or even understand them is something that many critics of the program have questioned. Thus far, 14 monkeys have died in the line of duty while more than 30 situations have been resolved completely successfully.