Cybertrons have permeated every corner of the galaxy; they are colonizers, first and foremost, and choose where they live and when. Cybertronian technology allows for time travel, and though "mucking around" in the events of the Great War itself is prohibited, it isn't always prevented. Chronicles set on Cybertron itself during the Beast Wars are set in the years 2300 (earth-time) and beyond. The Beast Wars on Earth itself were during approximately 4 million BC. Statistics for "show" regulars will be provided-play these characters if you want, or create your own. Have them interact with the "real" characters, or ignore that war entirely. Set a crossover chronicle in the regular World of Darkness (details are below for most possibilities); set it on another planet altogether and have your players create alien "beast" modes. Above all, enjoy this system and have fun with it.
This system is designed for those who are familiar with White Wolf roleplaying, and is not designed to be a replacement for the roleplaying books provided by White Wolf publications. Beast Wars fans and Transformers fans who want to give this system a try will still have to pick up a "real" White Wolf book or two. I recommend Werewolf and Vampire. Mage, Wraith', and Changeling will all work fine as examples of the system itself, but don't adapt as well to the information [included].