From the Publisher's Website:
Bloodworks is a generic RPG designed to create conflicted characters for a variety of genres. Though generic, Bloodworks is designed to be flavorful and to provide a character a constant threat - his own "dark side."
Vitally, there are two parts to each character: his Face and his Bane. A character's Face is what is usually seen in the game; it's every part of the character that he has worked on or picked up, his skills, occupation, and niche. A character's Bane is the part of him that tries to hold him back.
Each character occupies a distinct niche in the game, his/her Title. A Title implies something about the character; it should explain some of what he can do and his background. A good Title would be The Runaway Girl. The Title tells us what we need to know - the biggest factor in her background and perhaps some of her skills. It's slightly binding, but not too much. A poor Title would be The Fighter. "Fighter" is too general to be effective; a better Title would be The Barroom Brawler, The Jaded Gunman, or The Alleyway Knifer.
Characters have five attributes: Body, Agility, Intellect, Will, Charm. They also have a dark side to their character, their Bane, that has five attributes of its own: Malice, Instability, Self-Destruction, Ties, Doubt.
Action resolution is performed by rolling one twenty-sided die, adding the result to the appropriate attribute (along with any modifiers), and comparing against an opposed roll. A result that is at least double the opposed roll is a critical success.