Nome, Alaska, 1901. There's a gold rush on at the very end of the Earth, attracting every manner of ne'er-do-well and fiend from deranged Kuskokwagmiut to Wyatt Earp. And you, of course.
Frost Devils is a reskinning of Matt Snyder's excellent game Dust Devils. It can also serve as a really solid and historically meticulous resource guide to Nome at the turn of the last century for any game.