Well, we know where we’re going
But we don’t know where we’ve been.
And we know what we’re knowing.
But we can’t say what we’ve seen.
And we’re not little children.
And we know what we want.
And the future is certain.
Give us time to work it out.
-- "Road to Nowhere," The Talking Heads
The Illuminati has been working on methods of creating the next generation of humans, in a secret research facility. Some of these experiments have escaped and have wandered into a cabin in the woods near Boulder. The people in the cabin have found a book on the Kabala and cast a spell. They think the escapees are the result of the spell.
The spell has fractured time. The escapees have flashbacks that explain who they are and what they are. Also, something is coming from n-time, a part of time that is orthogonal to our own. The players must figure out how to defeat the creature from n-time using the Kabala, the secret Illuminati knowledge, and the enhanced humans.
If they succeed, then time is realigned so that it all never happened. If they fail, then time is realigned such that they are stuck in a dystopia where the Illuminati rules all with an iron fist.