From publisher blurb:
Diseases of the body can kill, but insanity can do worse. It can turn a hero into a cold and dispassionate sociopath, a trusted lover or best friend into something too like an animal for comfort. Heroes confronted by horrific aberrations and monsters from beyond reality sometime go mad from the experience, and even the boldest heroes can be driven to insanity by battlefield trauma. Insanity is a new threat that must be faced and overcome by heroes in Pathfinder Roleplaying Game campaigns. This product includes such dangers as Black Futility, Draconic Obsession, Dying Nostalgia, Dust Nihilism, Ergot Sickness, Mute Witness, Symbolic Compulsion, Temporal Isolation and Wretched Wilting.