From the back of the book:
In the high-flying world of Azure there is a special breed of genius. Shunned by their families, ignored by their peers, they are MAD SCIENTISTS. Their work will change the world... if they live long enough to finish it.
You Must Be Mad! contains detailed mad scientist NPCs, laboratory examples, new rules, and dozens of new science projects and plot hooks.
It also has background information on some of the covert organizations with a vested interest in mad science, stats for both mundane and fantastic creatures, and a rules expansion for cinematic fleet battles using Rapidfire rules.