Isis is a rule system based on West End Games' D6 System. In theory, the game would support any genre, but it is tooled to support the fantasy world of Isis. Characters have six Statistics (Dexterity, Knowledge, Body, Perception, Charisma, and Spirit) and a dice pool is associated with each. Racial limits apply to each Statistic. Characters also have Skills that are based upon a single Statistic. A lengthy list of Advantages and Disadvantages is provided. Characters may gain either Hero Points or Villainy Points depending on their actions. The conflict resolution system follows West End Games' D6 System closely and is a well-developed, rich environment with numerous options supported.