From publisher blurb:
The ISS Tranquility is plying the spacelanes of the Confederation. She's carrying a load of cargo and passengers and travelling through the New Haven systems, headed for the St. Sebastian wormhole gate. Up until now, it's been an uneventful voyage.
Rose Alverez, heiress, has disappeared. On a spaceship with very few hiding places. What's the crew of the Tranquilty to do?
In Space No One Can Hear You... is a playbook for the The Trouble with Rose rule system.