From the back of the book:
The HERO System rules are designed to handle any type of combat – whether it involves two groups of gun-wielding gangsters on a grimy inner city street, caped superheroes using energy bolts and a super-strength in a fight in outer space, Fantasy warriors and wizards wielding swords and spells against trolls and dragons, a blaster duel in the corridors of a starship, or even stranger forms of conflict. The basic rules in Chapter Two of the HERO System 5th Edition, Revised rulebook, combined with the more advanced or genre-specific rules in various HERO System books, allow you to fight just about any type of battle you can imagine.
To help your game run as smoothly and enjoyably as possible, The HERO System Combat Handbook compiles the combat rules from the HERO system 5th Edition, Revised rulebook and these supplements:
The Ultimate Brick
The Ultimate Martial Artist
Additionally, The HERO System Combat Handbook supplements that material with new rules, expanded and clarified rules, and other information so you have all the combat rules you need right at your fingertips!